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Strategic Leadership in Genomic Medicine

Consultant Pharmacist – Genomics

East NHS Genomic Medicine Service Alliance | Oct 2023 – Present

Working with the wider GMSA teams across the East of England network to deliver equitable patient access to genomic testing in the East of England and East Midlands.

• Lead regional and national pharmacy-led implementation projects in precision medicine and PGx (e.g. DPYD, TPMT testing)
• Developed strategies, business plans, and policy briefings for PGx testing aligned to MHRA, NICE and NHS England specifications and standards
• Liaised and collaborated with NHS Digital, genetics and pathology labs, regional networks, to enable equitable evidence-based biomarker access
• Presented impact data to GMSA executive boards, managed budgets and resource planning.
• Experienced using clinical and scientific databases and resources, relevant informatics tools.
• Co-Founded and leading regional East Genomics Pharmacy network.

Senior Pharmacist – Genomics Transformation Projects

East NHS Genomic Medicine Service Alliance | 2021 – Oct 2023 (PT)

Working with the wider GMSA teams across the EoE network to deliver equitable patient access to genomic testing in the East of England and East Midlands.

• Lead regional and national pharmacy-led implementation projects in precision medicine and PGx (e.g. DPYD, TPMT testing)
• Developed strategies, business plans, and policy briefings for PGx testing aligned to MHRA, NICE and NHS England specifications and standards
• Liaised and collaborated with NHS Digital, genetics and pathology labs, regional networks, to enable equitable evidence-based biomarker access
• Presented impact data to GMSA executive boards, managed budgets and resource planning.
• Experienced using clinical and scientific databases and resources, relevant informatics tools.
• Co-Founded and leading regional East Genomics Pharmacy network.

SME: Clinical and Tech Advisor

Datum Pharmacogenomics & AI | Dec 2023 – Present

Providing clinical strategic leadership, and translating clinical and drug development needs to develop a novel genomics and medicines Knowledge Graph Augmentation to solve PGx implementation with responsible use of generative artificial intelligence. Applications include precision medicine and PGx clinical decision support, drug development.

Senior Pharmacy Manager – Genomics

NHS England Genomics Unit – Part-time | 2022 – Oct 2023

Working towards delivering the NHS strategic commitments on genomics, building on the contributions of the 100,000 Genome Project, by encompassing genomics and biomarkers in routine clinical care. This will realise significant benefits and minimise medication toxicity in patient care. Driving pharmacy workforce in implementing personalised medicine with the Chief Pharmaceutical Officer and Chief Scientific Officer.

Developed or influenced several frameworks intersecting genomics and medicines, including:

• Data analytics to determine adherence to pharmacogenomic guidelines and outcome measures via NHS Digital
• Horizon scanning for new medicines informed by genomic biomarkers
• Influenced regulatory framework for biomarker inclusion in studies
• Developed implementation plans and evidence reviews for new tests
• Impact assessments for new biomarker / genomic test implementation
• Planning pharmacy and genomics workforce strategy and influencing senior stakeholders
• Initiated real-world proposals on data for biomarker impact and surrogate toxicity outcomes
• Designing milestones and supporting GMSA pharmacists to achieve business plan deliverables

Education Lead – Genomics Committee

UK Clinical Pharmacy Association | 2022 – Present. Informally since 2021.

Representing clinical pharmacists in national NHS England Pharmacy and Genomics education/workforce working group.

• Development workshops, webinar and presentation content and supporting its delivery to UKCPA members.
• Liaising with other clinical committees to deliver specialist content through their networks.
• Leading applications for new tests in the National Genomic Test Directory.
• Promoting engagement and networking through social media platforms.
• Developing content and media for conferences where UKCPA is represented.

Academic & Translational Research

Guest Lecturer and Researcher

University of Cambridge | 2019 – Present

Guest lecturer on postgraduate pharmacogenomics, including supervising assignments and dissertations. Contributed to the redesign of the structure of the pharmacogenetics module.

Member of Dr Timothy Hearn’s research lab on comparative chronomics, currently focused on biological clocks as biomarkers and defining chrono-pharmacogenomics as a novel, cost-effective precision medicine science. This includes autonomously developing my research and experiment methodology and strategy.

East Health Education England Pre-doctoral Clinical Academic Fellowship

2022 – 2023

Awarded one of five East of England Integrated Clinical Academic pre-doctoral bridging funding to develop my research skills and my research proposal towards doctoral studies.

• Fellowship in conjunction with University of Cambridge academic supervisor, University of Leicester Pharmacy Professor as mentor, and University of East Anglia.
• Training and development in scientific writing, computational methods, statistics, health research methodology development, epidemiology, patient & public and carer involvement, costing research projects, and others.

Advanced Clinical and Formulary Practice

Advanced Pharmacist – Medical Haematology

Cambridge University Hospitals NHSFT (PT) | Oct 2023 – Present

Providing an advanced clinical pharmacy service and leadership to haematology services and patients. Prescribing medication within scope of practice in thrombophilia and haemoglobinopathy.

Founded and leading GB-wide NHS Medical Haematology Pharmacy Network (42 members).

Lead Clinical Pharmacist – Formulary

Cambridge University Hospitals NHSFT | 2019 – 2022

On behalf of the Trust, responsible for the managed introduction of medicines to the Cambridgeshire system-wide medicines formulary. This includes secretarial responsibility for the Joint Drugs & Therapeutics committee and representing the trust at external prescribing and formulary groups to ensure safe, evidence-based and cost-effective use of medicines.

• Evaluating formulary submissions through critical appraisal of the evidence-base and cost-effectiveness has supported application of synthesising and reporting on existing literature.
• Consulting on formulary matters and applied evidence-based practice in diverse NHS settings.
• Interpreting and communicating complex, highly technical information.
• Displaying academic leadership as educational supervisor for juniors.
• Founded and leading GB-wide formulary pharmacist collaboration network (130+ members).

Specialist Clinical Rotational Pharmacist

Cambridge University Hospitals NHSFT | Aug 2015 – Jul 2019

Specialist Rotations:

• Surgery (vascular, colorectal, ophthalmology, plastics, ENT)
• Acute medicine
• Critical care and trauma
• Transplant
• Paediatrics (respiratory, neurology, TPN, gastroenterology)

Chief band 7 pharmacist. Provided advanced clinical pharmaceutical services and achieved the following:

• Delivered medication safety and prescribing training sessions to clinicians.
• Developed service development change management plan for the implementation of clinical pharmacists in Acute Medicine teams on the Elective Admissions Unit.
• Taught and mentored junior pharmacists, standardised induction training.
• Proposed an evidence-based, standardised medicines management/optimisation framework for prioritising and allocating clinical workload.
• Assisted in novel emergency department pharmacy service development and rota.
• Chief band 7 pharmacist role leading and representing peers and chairing meetings, developed training frameworks for each specialist rotation and rolling peer education sessions, modernised and redesigned pharmacy rota systems with informatics and metrics, assisted in pharmacy rotas SOP.
• Developed guidelines to align medication standards & practices across different ICUs.
• Developed guideline and library of standardised electronic smartforms for common clinical intervention scenarios such as TDM or high-risk drugs that changed Trust pharmacy practices across the board.
• Led in standardising transplant patient counselling through process modernisation.
• Audited specialist transplant pharmacist interventions to inform e-hospital system improvements and later develop an e-training package.
• Diploma tutor and line manager to junior pharmacists.

Clinical Rotational Pharmacist

Ipswich Hospitals NHST | 2014 – 2015

Military Pharmacist

Cypriot national guard | Jun 2017 – Oct 2017

Responsible for the seamless provision of pharmaceutical services in the central medical distribution centre to other military bases across Cyprus.

Achievements:

• Optimised the military formulary & medication contracts to cost-effective alternatives.
• Deputised in the absence of the Lieutenant and managed junior cadets for operations.
• Proactively facilitated improvements to informatics and operations processes.
• Assisted in combat first-aid training to recruits with military medics.

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📋 LLMS · LLMS Full